Carlon Brown scored 18 points to lead the Buffs to a 87-69 victory in front of 7,110 fans with the students still away on winter break. Four other Buffs finished in double figures.
Andre Roberson pulled down 12 rebounds against the league's best rebounding team, scored eight points and blocked two shots, helping Colorado overcome 17 turnovers against the rangy, athletic Huskies.
After falling behind 14-5 in the early going, the Buffs began to play together, especially on the defensive end. The score gradually turned in their favor and they held a 10-point lead and clearly had coach Lorenzo Romar and his team frustrated at halftime.
"I like how we handled our adversity tonight," CU coach Tad Boyle said. "It's not like we came out and just blew them out. We had to fight for it. I'm not ready to anoint ourselves conference champions. We're two games into an 18-game schedule. But I like the track we're on. I like the direction we're headed, but this thing is marathon."
He didn't get a lot of help from his teammates as the Huskies didn't share the ball and make the extra pass the way Romar hoped they would.
C.J. Wilcox came off the bench to score 19 for Washington, which has lost three times on the road this season.
"They were very efficient," Romar said of the Buffs. "We told our team they would be very efficient. We did things that were unexpected of us. We didn't guard like we should have, we didn't share the ball, things of that nature."